抑制素富集制剂（IEP）对雌性仓鼠的局部抗生育作用。
Local anti-fertility effect of inhibin-enriched preparation (IEP) in female hamsters.
作者信息
Bapat B V, Nandedkar T D, Sheth A R
出版信息
Contraception. 1984 Apr;29(4):367-73. doi: 10.1016/0010-7824(84)90070-2.
An inhibin-enriched preparation (IEP) involved in the regulation of follicle stimulating hormone (FSH) is known to play an important role in the normal ovarian cycle. In utero administration of 10 micrograms of IEP on day 3 of pregnancy completely prevented implantation in hamsters. No toxic effect of IEP was observed on the blastocysts as indicated by the dye exclusion test performed with Trypan blue. Thus, the results of the present study indicate an extra-pituitary site of action for the anti-implantation effect of IEP.
一种参与调节促卵泡激素（FSH）的富含抑制素的制剂（IEP），已知在正常卵巢周期中起重要作用。在怀孕第3天对仓鼠子宫内给予10微克IEP可完全阻止着床。用台盼蓝进行的染料排除试验表明，IEP对胚泡没有毒性作用。因此，本研究结果表明IEP抗着床作用的垂体外作用位点。
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