Matsushima Y, Jones R L, King E G, Moysa G, Alton J D
Chest. 1984 Aug;86(2):184-8. doi: 10.1378/chest.86.2.184.
Pulmonary function and arterial blood gases were measured in 35 patients undergoing routine diagnostic flexible fiberoptic bronchoscopy (FFB) either through an 8-mm endotracheal tube (ETT) or transnasally in order to investigate whether FFB changes lung function in a way which may explain why hypoxemia commonly occurs during this procedure. In these patients with moderate airway obstruction, functional residual capacity (FRC) increased significantly after inserting the ETT, after placing the FFB in the airway through the ETT, and after inserting the flexible bronchoscope transnasally. The mean increase in FRC was 30 percent in the intubated group before FFB insertion and 17 percent in the transnasal group. Removal of the FFB and ETT caused FRC to return toward the control value. Insertion of the ETT-FFB combination or transnasal FFB did not change PaO2 substantially, although following the examination, PaO2 was decreased significantly in the transnasal group but not in the intubated group. The PaO2 decreased significantly in both groups following removal of the ETT and transnasal FFB. These results suggest that placement of an FFB or ETT-FFB combination in the airway in spontaneously breathing subjects elevates FRC.
对35例接受常规诊断性可弯曲纤维支气管镜检查（FFB）的患者进行了肺功能和动脉血气测量，这些患者要么通过8毫米气管内插管（ETT），要么经鼻进行检查，以调查FFB是否以某种方式改变肺功能，从而解释为什么在此过程中低氧血症常见。在这些中度气道阻塞的患者中，插入ETT后、通过ETT将FFB放入气道后以及经鼻插入可弯曲支气管镜后，功能残气量（FRC）均显著增加。在FFB插入前，插管组FRC的平均增加幅度为30%，经鼻组为17%。移除FFB和ETT后，FRC恢复至接近对照值。插入ETT-FFB组合或经鼻FFB对动脉血氧分压（PaO2）没有实质性改变，尽管检查后，经鼻组的PaO2显著降低，而插管组未降低。移除ETT和经鼻FFB后，两组的PaO2均显著降低。这些结果表明，在自主呼吸的受试者气道中放置FFB或ETT-FFB组合会提高FRC。
