Webb M L, Wallace J P, Hamill C, Hodgson J L, Mashaly M M
Endocr Res. 1984;10(1):27-38. doi: 10.1080/07435808409046763.
The purpose of this study was to determine alterations in testosterone concentration in women during 2 hours of moderate intensity running, and to compare this response to that seen in men. Maximal oxygen uptake (VO2 max) and anaerobic threshold (AT) were determined in 11 men and 9 women. These subjects subsequently ran for 2 hours on a motor-driven treadmill at 10% below the AT which was approximately 70% VO2 max. Blood samples were drawn at 0, 30, 60, 90 and 120 minutes of exercise and testosterone was measured by specific radioimmunoassay. Serum testosterone concentration was significantly increased (41%, P less than .01) after 30 minutes of exercise in the men. In the women, testosterone was not significantly increased from pre-exercise concentrations until 120 minutes of exercise (48%, P less than .01). At this time the testosterone concentration in the men had decreased and was no longer significantly elevated from the pre-exercise concentration. The magnitude of the increases in serum testosterone concentration can probably be accounted for by decreases in the metabolic clearance rate of sex-steroids known to occur during exercise. Differences in the testosterone response between men and women during prolonged aerobic exercise are of interest and may imply that different mechanisms of control are involved.
本研究的目的是确定女性在进行两小时中等强度跑步期间睾酮浓度的变化，并将这种反应与男性的反应进行比较。对11名男性和9名女性测定了最大摄氧量（VO2 max）和无氧阈（AT）。这些受试者随后在电动跑步机上以低于无氧阈10%的强度跑步两小时，该强度约为最大摄氧量的70%。在运动的0、30、60、90和120分钟时采集血样，并通过特异性放射免疫测定法测量睾酮。男性在运动30分钟后血清睾酮浓度显著升高（41%，P<0.01）。在女性中，直到运动120分钟时睾酮才从运动前浓度显著升高（48%，P<0.01）。此时男性的睾酮浓度已经下降，不再比运动前浓度显著升高。血清睾酮浓度升高的幅度可能是由于运动期间已知的性类固醇代谢清除率降低所致。男性和女性在长时间有氧运动期间睾酮反应的差异令人感兴趣，可能意味着涉及不同的控制机制。
