Temkin N R, Davis G R
Epilepsia. 1984 Aug;25(4):450-6. doi: 10.1111/j.1528-1157.1984.tb03442.x.
This study examines the effects of major life events, daily hassles and uplifts, and daily stress levels as they increase or decrease the risks of having seizures and estimates risk ratios for specific stressors and perceived stress levels. Utilizing a prospective design, 12 adults with severe epilepsy monitored the occurrence of seizures, stressors, and stress levels over a 3-month period. In within-individual analyses, high stress levels and stressful events were associated with more frequent seizures for most participants. The association between higher stress levels and increased seizures was confirmed in group analyses. This study provides empirical evidence of the association between stress and seizures and describes the use of a statistical model that is useful for investigating risk factors as they influence physical and mental illness.
本研究考察了重大生活事件、日常烦扰与愉悦之事以及日常压力水平对癫痫发作风险增加或降低的影响，并估算了特定应激源和感知压力水平的风险比。采用前瞻性设计，12名患有严重癫痫的成年人在3个月内监测癫痫发作、应激源和压力水平的发生情况。在个体内部分析中，对大多数参与者而言，高压力水平和应激事件与更频繁的癫痫发作相关。在组间分析中证实了较高压力水平与癫痫发作增加之间的关联。本研究为压力与癫痫发作之间的关联提供了实证证据，并描述了一种统计模型的应用，该模型有助于调查影响身心健康的风险因素。
