Rivera R, Gaitan J R, Ortega M, Flores C, Hernandez A
Fertil Steril. 1984 Aug;42(2):228-32.
The effects of a 6-month contraceptive system of biodegradable norethisterone (NET) implants on the menstrual cycle, estradiol and progesterone levels, the presence of side effects, its contraceptive effectiveness, and the NET levels achieved were studied in a group of nine women. There was practically no disruption of the menstrual cycle and no important side effects. Ovulation was inhibited in four subjects, and another four subjects remained ovulatory. In all the subjects a cyclic secretion of estradiol was maintained. No pregnancies occurred. The circulatory levels of NET were very stable throughout the 6-month period of implant use.
在一组9名女性中,研究了可生物降解的炔诺酮(NET)植入物6个月避孕系统对月经周期、雌二醇和孕酮水平、副作用的出现、避孕效果以及所达到的NET水平的影响。月经周期几乎没有受到干扰,也没有严重的副作用。4名受试者的排卵受到抑制,另外4名受试者仍有排卵。所有受试者的雌二醇都保持周期性分泌。没有发生妊娠。在植入物使用的6个月期间,NET的循环水平非常稳定。