Pinget M, Wirion R, Blickle J F, Dorner M
Diabete Metab. 1984 May;10(2):85-90.
The authors have treated 6 diabetic patients for at least 3 months with subcutaneous insulin infusion system using a peristaltic pump and a highly stable preparation (U 100 with physiological pH). Correct diabetic control was achieved in each case, during a cumulative period of 44 patients-months. The high stability of the insulin preparation allows a prolonged insulin storage in the pump, from 2 to 3 months without any change in the hypoglycaemic effect of the solution. Advantages and risks of this method are discussed.
作者使用蠕动泵和高度稳定的制剂(生理pH值的U100),对6例糖尿病患者进行了至少3个月的皮下胰岛素输注治疗。在累计44个患者月的时间里,每例患者均实现了正确的血糖控制。胰岛素制剂的高稳定性使得胰岛素在泵中可长时间储存,长达2至3个月,而溶液的降血糖效果无任何变化。本文讨论了该方法的优点和风险。