Paulsen K D, Strohbehn J W, Hill S C, Lynch D R, Kennedy F E
Int J Radiat Oncol Biol Phys. 1984 Jul;10(7):1095-107. doi: 10.1016/0360-3016(84)90183-4.
In this paper we report on theoretical calculations for the temperature distributions produced by an rf magnetic induction device that is placed concentrically about the long axis of the patient. A two-dimensional, axi-asymmetric, inhomogeneous patient model was used in conjunction with a numerical moment method for calculating the electric fields in the tissues of the model and a numerical finite element method for calculating the resulting temperature distributions. The electric fields and the absorbed power per unit volume of tissue were calculated for both a thorax and viscera model, each of which included a tumor volume. The absorbed power values were input into the bioheat transfer equation and the temperature distributions were calculated for a wide range of blood flow rates. Based on the steady-state and transient results, our computer simulations predict poor therapeutic temperature profiles for tumors embedded deeply in the thorax and viscera. This heating technique appears to produce significant therapeutic volumes in superficial tumors located not greater than 7 cm in depth. These theoretical calculations should aid the clinician in the evaluation of induction heating devices for their effectiveness in heating deep-seated and superficial tumors.
在本文中，我们报告了关于一种射频磁感应装置所产生温度分布的理论计算，该装置围绕患者的长轴同心放置。使用二维、轴对称非均匀患者模型，结合数值矩量法计算模型组织中的电场，以及数值有限元法计算由此产生的温度分布。针对胸部和内脏模型计算了电场和每单位组织体积吸收的功率，每个模型都包含一个肿瘤体积。将吸收的功率值输入生物热传递方程，并针对广泛的血流速率计算温度分布。基于稳态和瞬态结果，我们的计算机模拟预测，对于深埋在胸部和内脏中的肿瘤，治疗温度分布不佳。这种加热技术似乎能在深度不超过7厘米的浅表肿瘤中产生显著的治疗体积。这些理论计算应有助于临床医生评估感应加热装置对深部和浅表肿瘤加热的有效性。
