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锡兰钩虫在金黄仓鼠体内的感染性、存活期及繁殖力研究。

Studies on infectivity, longevity and fecundity of Ancylostoma ceylanicum in golden hamsters.

作者信息

Visen P K, Katiyar J C, Sen A B

出版信息

J Helminthol. 1984 Jun;58(2):159-63. doi: 10.1017/s0022149x00028698.

DOI:10.1017/s0022149x00028698
PMID:6747259
Abstract

Ancylostoma ceylanicum is a new introduction as an experimental hookworm model. Information on the biology of this parasite in its laboratory host--the golden hamster, is meagre. Its infectivity, longevity and fecundity were studied to obtain relevant information especially on vulnerable points in the maintenance and continuation of the infection. 100% infectivity was obtained with an inoculum of 60 larvae per animal. Maximum numbers of parasites were harboured from day 15 to day 18 after infection and thereafter gradually declined. Approximately 10% of the worms were still present at the end of the third month of infection. The in vitro release of eggs in a 24-hour period by one female nematode peaked from day 25 to day 39, a second rise occurred in day 70 after infection.

摘要

锡兰钩虫作为一种新型实验性钩虫模型被引入。关于这种寄生虫在其实验室宿主——金黄仓鼠体内的生物学信息很少。对其感染性、寿命和繁殖力进行了研究,以获取相关信息,特别是关于感染维持和延续中的薄弱环节。每只动物接种60条幼虫时感染率达100%。感染后第15天至第18天寄生虫数量最多,此后逐渐下降。感染第三个月末仍有约10%的蠕虫存在。一条雌线虫在24小时内体外产卵量在感染后第25天至第39天达到峰值,在第70天出现第二次上升。

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引用本文的文献

1
Comparison of percutaneous vs oral infection of hamsters with the hookworm Ancylostoma ceylanicum: Parasite development, pathology and primary immune response.经皮与口服感染仓鼠旋毛虫:寄生虫发育、病理学和初级免疫反应的比较。
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2
Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster.金黄叙利亚仓鼠感染锡兰钩虫过程中的宿主细胞因子产生、淋巴细胞增殖及抗体反应。
Infect Immun. 2005 Jun;73(6):3402-7. doi: 10.1128/IAI.73.6.3402-3407.2005.
3
Oral transfer of adult Ancylostoma ceylanicum hookworms into permissive and nonpermissive host species.
将成年锡兰钩虫经口转移至易感和非易感宿主物种。
Infect Immun. 2003 Apr;71(4):1880-6. doi: 10.1128/IAI.71.4.1880-1886.2003.