Borroni E
J Neurochem. 1984 Sep;43(3):795-8. doi: 10.1111/j.1471-4159.1984.tb12801.x.
The role of creatine phosphate and adenosine triphosphate, as high energy phosphate sources, has been investigated during the discharge and recovery of the electric organ of Torpedo. ATP serves as the immediate source of energy for the biochemical process supporting the electrical activity of the electric organ. Under repetitive stimulation, when the energy demands exceed production, ATP levels are maintained constant at the expense of creatine phosphate. Only when the reservoir of creatine phosphate is depleted do the levels of ATP decrease, and this point corresponds to the state of maximal fatigue of the electric organ. Recovery studies show that the electric organ rapidly recovers the capacity to respond to single pulse stimuli. This recovery is statistically related to the recovery of the levels of ATP and acetylcholine. However, in this phase, the fatiguability of the electric organ is very high since its energy reservoir is still depleted. The complete recovery of the electric organ requires several hours and is closely related to the restoration of the levels of creatine phosphate.
磷酸肌酸和三磷酸腺苷作为高能磷酸源，在电鳐电器官放电和恢复过程中的作用已得到研究。三磷酸腺苷作为支持电器官电活动的生化过程的直接能量来源。在重复刺激下，当能量需求超过产生量时，三磷酸腺苷水平以磷酸肌酸为代价维持恒定。只有当磷酸肌酸储备耗尽时，三磷酸腺苷水平才会下降，而这一点对应于电器官最大疲劳状态。恢复研究表明，电器官能迅速恢复对单脉冲刺激的反应能力。这种恢复在统计学上与三磷酸腺苷和乙酰胆碱水平的恢复相关。然而，在此阶段，电器官的易疲劳性非常高，因为其能量储备仍然耗尽。电器官的完全恢复需要几个小时，并且与磷酸肌酸水平的恢复密切相关。
