Koutlidis R M, de Recondo J, Bathien N
J Neurol Sci. 1984 May;64(2):183-91. doi: 10.1016/0022-510x(84)90036-4.
Conduction in the proximal segment of the sciatic nerve was assessed by recording the latencies of M and H responses from soleus muscle, in the distal segment by comparing the latencies of M waves from the abductor hallucis muscle, obtained by stimulating the tibial nerve in the popliteal fossa and at the ankle. Data from 30 patients with amyotrophic lateral sclerosis (ALS) were compared with an age-matched group of healthy subjects. We observed an increase in the difference between the latencies of M and H responses from soleus, and a lengthening of the distal latency of the M wave from abductor hallucis. The motor conduction velocity of the tibial nerve was preserved. The functional significance of the data are discussed. It is suggested that they indicate a slowing of conduction in the proximal segment of the sciatic nerve and that they can be correlated with pathological findings in proximal nerves in ALS and in the experimental anterior horn cell disorder.
通过记录比目鱼肌的M波和H反射潜伏期来评估坐骨神经近端节段的传导，通过比较在腘窝和踝关节处刺激胫神经时拇展肌M波的潜伏期来评估坐骨神经远端节段的传导。将30例肌萎缩侧索硬化症（ALS）患者的数据与年龄匹配的健康受试者组进行比较。我们观察到比目鱼肌M波和H反射潜伏期之间的差异增加，以及拇展肌M波远端潜伏期延长。胫神经的运动传导速度保持不变。讨论了这些数据的功能意义。提示这些数据表明坐骨神经近端节段传导减慢，并且可以与ALS及实验性前角细胞疾病中近端神经的病理发现相关联。
