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海平面实际气压与肺泡及动脉血氧分压之间的关系:3054名患与未患尘肺病煤矿工人的相关性(作者译)

[Relation between actual barometric pressure at sea level and alveolar and arterial pO2: correlations in 3,054 coal workers with and without pneumoconiosis (author's transl)].

作者信息

Sohnius J, Smidt U, Worth G

出版信息

Respiration. 1978;36(3):138-44. doi: 10.1159/000193938.

Abstract

The correlation between barometric pressure and arterial oxygen pressure has been investigated in 3,054 coal miners. Furthermore, the correlation between alveolar oxygen pressure and alveolar-arterial oxygen pressure difference and barometric pressure has been investigated in 1,669 coal miners. For low and for high pO2a there are significant correlations to barometric pressure, in particular for the young age groups. PO2A and AaDO2 show closer correlations to barometric pressure in the middle range of pO2a (65--84 mm Hg). This points to different regulating mechanisms. A correction with a uniform factor is not possible and, for clinical purposes, unnecessary, since the influence of changing barometric pressure on pO2a is only about 1--3 mm Hg.

摘要

对3054名煤矿工人的大气压力与动脉血氧压力之间的相关性进行了研究。此外,还对1669名煤矿工人的肺泡氧压力、肺泡-动脉氧分压差与大气压力之间的相关性进行了研究。对于低和高动脉血氧分压(pO2a),其与大气压力存在显著相关性,特别是在年轻年龄组中。在动脉血氧分压的中等范围(65-84mmHg)内,动脉血氧分压(PO2A)和肺泡-动脉氧分压差(AaDO2)与大气压力的相关性更密切。这表明存在不同的调节机制。用一个统一的因素进行校正既不可能,也无临床必要性,因为大气压力变化对动脉血氧分压的影响仅约为1-3mmHg。

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