Gavras I, Gavras H, Chobanian A V, Tifft C P, Melby J C, Jick H
Clin Exp Hypertens A. 1982;4(7):1097-106. doi: 10.3109/10641968209060777.
Plasma renin activity, aldosterone and norepinephrine levels were determined in 247 ambulatory hypertensive patients divided into young, middle aged, and old groups. PRA and the increase of PRA after furosemide were higher in the younger; NE was higher in the old group. Some relationships may be inherent in aging and not necessarily confined to hypertensives. This may explain discrepancies between reports by investigators who studied homogenous groups classified in different ways.
对247例门诊高血压患者进行分组（分为青年组、中年组和老年组），测定其血浆肾素活性、醛固酮和去甲肾上腺素水平。青年组的血浆肾素活性（PRA）以及速尿后PRA的升高幅度较高；老年组的去甲肾上腺素（NE）水平较高。某些关系可能是衰老所固有的，不一定局限于高血压患者。这可能解释了不同研究者对以不同方式分类的同质组进行研究时报告结果之间的差异。
