Scannapieco F A, Guerina N G, Goldmann D A
Infect Immun. 1982 Aug;37(2):830-2. doi: 10.1128/iai.37.2.830-832.1982.
Neonatal rats fed three strains of Escherichia coli K1 at birth had bacteremia rates of 29 to 81%; negligible bacteremia was seen with K92 and an unencapsulated strain. Despite this marked difference in virulence, K1, K92, and the unencapsulated strain all promptly, reliably, and stably colonized the entire alimentary tract, from pharynx to colon.
出生时喂食三种大肠杆菌K1菌株的新生大鼠菌血症发生率为29%至81%;而K92和一种无荚膜菌株引起的菌血症可忽略不计。尽管毒力存在显著差异,但K1、K92和无荚膜菌株都能迅速、可靠且稳定地定殖于从咽部到结肠的整个消化道。