Okumori M, Watanabe R, Samejima M, Ogata S, Ito T
Jpn J Surg. 1982;12(4):280-5. doi: 10.1007/BF02469562.
A 22-year-old Japanese man with bilateral renal artery stenosis associated with hypertension underwent successful surgery of simultaneous bilateral renal artery reconstruction under conditions of intraoperative renal perfusion with St. Thomas Hospital solution which is used for cardioplegia in open heart surgery. Circulation in the left kidney was interrupted for 58 minutes and that of the right kidney for 35 minutes. The patient fully recovered with no serious impairment of renal function. In addition to these stenotic lesions of the renal artery, there were medial necrosis of the aorta and fibromuscular dysplasia of the superior mesenteric artery. Administration of SQ14,225, an angiotensin I converting enzyme inhibitor, was effective in controlling hypertension during the preoperative period.
一名22岁患有双侧肾动脉狭窄并伴有高血压的日本男性,在术中使用用于心脏直视手术心肌停搏的圣托马斯医院溶液进行肾灌注的情况下,成功接受了双侧肾动脉同期重建手术。左肾血流阻断58分钟,右肾血流阻断35分钟。患者完全康复,肾功能未受到严重损害。除了这些肾动脉狭窄病变外,还存在主动脉中层坏死和肠系膜上动脉纤维肌发育异常。术前使用血管紧张素I转换酶抑制剂SQ14,225有效控制了高血压。