Miyake A, Sakumoto T, Aono T, Kawamura Y, Maeda T, Kurachi K
Obstet Gynecol. 1982 Oct;60(4):444-9.
The distribution and content of luteinizing hormone-releasing hormone (LH-RH) in human placental tissues were detected by enzymatic antibody and immunofluorescence techniques. Anti-LH-RH was taken up strongly by cytotrophoblasts and the villous stroma at 8 weeks of pregnancy; the uptake decreased with the progress of pregnancy. Anti-LH-RH was not taken up at all by syncytiotrophoblasts throughout pregnancy. These findings suggest that LH-RH is synthesized in the cytotrophoblast and villous stroma. The role of placental LH-RH in the synthesis of human chorionic gonadotropin is discussed.
采用酶抗体和免疫荧光技术检测了人胎盘组织中促黄体生成激素释放激素（LH-RH）的分布和含量。在妊娠8周时，细胞滋养层细胞和绒毛间质对抗LH-RH摄取强烈；随着妊娠进展摄取减少。在整个妊娠期间，合体滋养层细胞对抗LH-RH完全不摄取。这些发现提示LH-RH是在细胞滋养层细胞和绒毛间质中合成的。文中讨论了胎盘LH-RH在人绒毛膜促性腺激素合成中的作用。
