Yerushalmi A, Karman S, Lwoff A
Proc Natl Acad Sci U S A. 1982 Aug;79(15):4766-9. doi: 10.1073/pnas.79.15.4766.
Ninety-five patients with documented perennial allergic rhinitis have been treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of one series of three 30-min insufflations of humidified air at 43 degrees C at a 2-hr interval. In the active treatment group, 75% (P less than 0.00003) and 68% (P less than 0.00001) of the patients were free of symptoms 1 week and 1 month, respectively, after treatment, compared with a 28% and 17% response in the placebo group. We conclude that local hyperthermia is effective in the treatment of perennial allergic rhinitis.
在一项随机双盲试验中,对95例确诊为常年性变应性鼻炎的患者进行了鼻腔局部热疗。治疗包括一系列三次,每次间隔2小时,用43摄氏度的湿化空气吹入鼻腔30分钟。在积极治疗组中,治疗后1周和1个月时分别有75%(P<0.00003)和68%(P<0.00001)的患者无症状,而安慰剂组的缓解率分别为28%和17%。我们得出结论,局部热疗对常年性变应性鼻炎有效。