Rosental R, Babarykin D, Fomina O, Smelters G, Valiniece M, Baumann V
Z Urol Nephrol. 1982 Jun;75(6):393-9.
The dynamic of indices changes of phosphorus treatment with nefrons in 16 patients after kidney transplantation was studied. The transitory hypophosphatemia accompanied with urine was typical in the majority of patients. The decrease of reabsorption and elevation of phosphorus clearance were noted. In a number of cases the phosphatemia level was increased due to reduction of prednisolone doses. It was experimentally revealed that prednisolone reduces the phosphorus absorption in intestine at 25% and the treatment by 1,25-dihydroxy-vitamin D3 and 1 alpha-hydroxyvitamin D3 promotes the normalization of this process.
对16例肾移植患者使用肾宁进行磷治疗时指标变化的动态进行了研究。大多数患者典型地出现伴有尿液的短暂性低磷血症。观察到重吸收减少和磷清除率升高。在一些病例中,由于泼尼松龙剂量减少,血磷水平升高。实验表明,泼尼松龙使肠道磷吸收降低25%,而使用1,25 - 二羟维生素D3和1α - 羟维生素D3进行治疗可促进该过程的正常化。