Coraim F, Duma S, Helmer F, Ilias W, Laczkovics A, Semsroth M, Haider W
Acta Med Austriaca. 1982;9(3):85-92.
After a brief comment on the origin and a summing up of types of postoperative cardiac arrhythmias in open heart surgery, mainly the therapy of these arrhythmias is discussed Besides drug therapy (antiarrhythmica) and cardioversion resp. pacing especially the possibility of a metabolic therapy is presented. In the postoperative phase after the trauma by the operation with the heart lung machine - which is similar to the shock phase after a myocardial infarction - a disordered energy metabolism with a decreased effectiveness of insulin occurs. It exists a diminished intracellular potassium-shifting, which causes an insufficient myocardial cell membrane potential. By means of exogenous high insulin and potassium supply with glucose infusion the potassium-shifting is improved, the FFA-level is lowered and the incidence of arrhythmias is reduced as sinusrhythm is induced.
在简要评论了心脏直视手术中术后心律失常的起源并总结其类型之后,主要讨论了这些心律失常的治疗方法。除了药物治疗(抗心律失常药物)和心脏复律及起搏外,特别介绍了代谢疗法的可能性。在使用心肺机进行手术造成创伤后的术后阶段——这类似于心肌梗死后的休克阶段——会出现能量代谢紊乱,胰岛素有效性降低。存在细胞内钾转运减少的情况,这会导致心肌细胞膜电位不足。通过外源输注高剂量胰岛素、钾和葡萄糖,可改善钾转运,降低游离脂肪酸水平,并诱导窦性心律,从而降低心律失常的发生率。