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Am J Physiol. 1982 Dec;243(6):E427-42. doi: 10.1152/ajpendo.1982.243.6.E427.
The direction of pituitary blood flow, the amount of pituitary blood flow, its regional control, and the role of the median eminence microcirculation are the subjects of this review. Present concepts of pituitary blood flow are focused almost entirely on its direction and arouse from studies of pituitary vascular anatomy performed almost 50 years ago. The development of new anatomic techniques has led to a reappraisal of pituitary angioarchitecture, stimulated physiological studies to clarify the pattern of blood flow within the entire gland, and led to a reappraisal of accepted concepts of directional pituitary blood flow. The availability of techniques to accurately measure organ blood flow has permitted study of pituitary blood flow; and, when combined with knowledge of pituitary anatomy, the application of these techniques promises to provide a means to develop insight into control of the mechanisms by which chemical messengers are delivered to the pituitary to control its function. New anatomic techniques promise to develop new understanding of the three-dimensional arrangement of median eminence microvasculature and yield new concepts of blood flow regulation within the median eminence that can be tested by physiological means.
垂体血流的方向、垂体血流量、其区域控制以及正中隆起微循环的作用是本综述的主题。目前关于垂体血流的概念几乎完全集中在其方向上,并且源于近50年前进行的垂体血管解剖学研究。新解剖技术的发展导致了对垂体血管结构的重新评估,激发了生理学研究以阐明整个腺体内的血流模式,并导致了对公认的垂体定向血流概念的重新评估。准确测量器官血流的技术的可用性使得对垂体血流的研究成为可能;并且,当与垂体解剖学知识相结合时,这些技术的应用有望提供一种手段,以深入了解化学信使传递到垂体以控制其功能的机制。新的解剖技术有望对正中隆起微血管的三维排列产生新的认识,并产生正中隆起内血流调节的新概念,这些概念可以通过生理学方法进行验证。