Noguchi K, Ifuku H, Ohe Y, Okamoto T, Fujita S, Kanamuru A, Nagai K, Kai S, Hara H, Uchino H, Yamagishi S, Yoshida Y
Scand J Haematol. 1982 Oct;29(4):299-303. doi: 10.1111/j.1600-0609.1982.tb00598.x.
A 16-year-old girl with severe aplastic anaemia was successfully treated with retransplantation of bone marrow from an HLA-identical sibling after rejection of the first transplantation from the same donor. Cyclophosphamide was used for the first transplantation and cyclophosphamide, 300 rad total-body irradiation and antilymphocyte globulin were used for the second transplantation. Permanent engraftment was achieved after the retransplantation with normalization of haemopoiesis, which has lasted for over 17 months. The patient is now in excellent clinical condition with minimal signs of chronic graft versus host disease.
一名16岁的重症再生障碍性贫血女孩，在首次接受来自同一供者的骨髓移植出现排斥反应后，成功地接受了来自 HLA 配型相同同胞的骨髓再次移植。第一次移植使用了环磷酰胺，第二次移植使用了环磷酰胺、300拉德全身照射和抗淋巴细胞球蛋白。再次移植后实现了永久性植入，造血功能恢复正常，且已持续超过17个月。患者目前临床状况良好，慢性移植物抗宿主病迹象轻微。
