Rost A, Molzahn M, Brosig W, Fiedler U
Urologe A. 1982 Sep;21(5):299-305.
In this investigation, our own long-term results after kidney transplantation were compared with those in literature, and the influence of recent findings on the survival rate of patients and transplants was analyzed. In 217 kidney transplant patients, the 5 and 9-year-patient survival rate was calculated at 58% and 45% respectively. The 9-year-transplant function rate was 38%. Analogous results can be derived from collective international and European statistics. The long-term patient survival rate after successful transplantation shows better results than comparable statistics of hemodialysis treatment. Analysis of the results fractionated into the years 1970 to 1974, 1975 to 1977 and 1978 to 1981 shows a continuous improvement in the survival rate of patients and transplants. This improvement of results can be attributed to the reduction of surgical complications with increasing experience and particularly to knowledge recently gained in the field of transplantation immunology (compatibility in the HLA-A/B and -DR system, preoperative blood transfusions) and immunosuppression (reduction of steroid doses, supplementary ATG and cyclosporin A medication).
在本研究中，我们将肾移植后的长期结果与文献中的结果进行了比较，并分析了近期研究结果对患者及移植肾存活率的影响。在217例肾移植患者中，计算得出5年和9年的患者存活率分别为58%和45%。9年的移植肾功能率为38%。类似的结果可从国际和欧洲的总体统计数据中得出。成功移植后的长期患者存活率比血液透析治疗的可比统计数据显示出更好的结果。将结果按1970年至1974年、1975年至1977年以及1978年至1981年进行分类分析，结果显示患者及移植肾的存活率持续提高。结果的改善可归因于随着经验增加手术并发症的减少，特别是归因于移植免疫学领域（HLA-A/B和-DR系统的相容性、术前输血）和免疫抑制（类固醇剂量的减少、补充抗胸腺细胞球蛋白和环孢素A药物治疗）方面最近获得的知识。
