Jonzon A, Sedin G
Acta Physiol Scand. 1982 Aug;115(4):415-9. doi: 10.1111/j.1748-1716.1982.tb07099.x.
To determine the lowest continuous positive airway pressure (CPAP) at which breathing becomes regular and to determine whether the phrenic nerve activity changes simultaneously, breathing pattern and phrenic nerve activity were studied in spontaneously breathing newborn lambs at various levels of CPAP. A CPAP of 0.25 kPa decreased the variability of phrenic burst interval, i.e. made the breathing regular. This CPAP also increased the mean impulse frequency within the phrenic nerve bursts, indicating greater inspiratory activity. A high CPAP did not offer any further advantages to the breathing pattern or to the inspiratory activity.
为了确定能使呼吸变得规律的最低持续气道正压（CPAP）水平，并确定膈神经活动是否同时发生变化，我们在不同CPAP水平下对自主呼吸的新生羔羊的呼吸模式和膈神经活动进行了研究。0.25 kPa的CPAP降低了膈神经爆发间隔的变异性，即使呼吸变得规律。该CPAP还增加了膈神经爆发内的平均冲动频率，表明吸气活动增强。高CPAP对呼吸模式或吸气活动没有进一步的益处。
