Tsementzis S A, Harris P, Loizou L A
Acta Neurochir (Wien). 1982;65(3-4):153-66. doi: 10.1007/BF01405841.
The intracranial pressure (ICP) was monitored in a number of patients who were being treated by mechanical ventilation for head injury. The effect on the pressure of routine nursing procedures was studied. Fourteen out of thirty-three cases (group 1) showed small reversible rises in ICP during suction, insertion of a N/G tube, or i.m. injections. These were associated with similar small increases in intrathoracic pressure and small fluctuations in arterial blood pressure. These rises were effectively treated with additional doses of relaxants. In a small group of patients (group 2) irreversible intracranial hypertension was induced by some of these stimuli, but did not respond to the administration of more relaxants, although sedatives such as papaveretum reduced it in some cases, but only slightly.
对一些因头部受伤接受机械通气治疗的患者进行了颅内压（ICP）监测。研究了常规护理操作对颅内压的影响。33例患者中的14例（第1组）在吸痰、插入鼻胃管或肌内注射期间，颅内压出现小幅度的可逆性升高。这些升高与胸内压的类似小幅升高以及动脉血压的小波动有关。额外剂量的松弛剂有效地治疗了这些升高。在一小部分患者（第2组）中，这些刺激中的一些诱发了不可逆的颅内高压，但对更多松弛剂的给药无反应，尽管诸如吗啡之类的镇静剂在某些情况下使其有所降低，但降幅很小。
