di Fronzo G, Bertuzzi A, Ronchi E
Tumori. 1978 Jun 30;64(3):259-66. doi: 10.1177/030089167806400303.
The evaluation of the data is an important step in performing the estrogen receptor test. For this reason an effort has been made to derive a more reliable threshold criteria. Among the parameters considered, Xo, Ka, and BI%, only the former 2 appear to be suitable to allow a proper evaluation of the results. From the analysis of different types of carcinomatous or normal breast specimens, limit values of these parameters have been recovered for positivity and negativity of the estrogen receptor test. We found all the samples showing Ka less than 1.5 x 10(9) M-1 or Xo less than 5 fmol/mg proteins to be negative, those characterized by low values of both the parameters were borderline, and all the remaining ones were positive.
数据评估是进行雌激素受体检测的重要步骤。因此，人们努力得出更可靠的阈值标准。在所考虑的参数Xo、Ka和BI%中，只有前两个参数似乎适合对结果进行恰当评估。通过对不同类型的癌性或正常乳腺标本进行分析，已得出这些参数用于雌激素受体检测阳性和阴性的极限值。我们发现，所有Ka小于1.5×10⁹ M⁻¹或Xo小于5 fmol/mg蛋白质的样本均为阴性，两个参数值均较低的样本为临界值，其余所有样本均为阳性。
