Lijnen P, Fagard R, Staessen J, Amery A
J Appl Physiol Respir Environ Exerc Physiol. 1982 Oct;53(4):891-4. doi: 10.1152/jappl.1982.53.4.891.
Plasma prostaglandins (PGE and PGF alpha), catecholamine concentration, and plasma renin activity (PRA) were measured during an uninterrupted graded exercise test on the bicycle ergometer in 11 hypertensive patients. Blood was withdrawn from the brachial and pulmonary arteries after 30 min of recumbent rest, after 15 min of rest sitting, and at the final work load of the exercise test, which averaged 143 +/- 16.5 W. Exercise did not provoke a significant change in these plasma PGE or PGF alpha concentrations, whereas a rise (P less than 0.001) in arterial PRA and (nor)epinephrine concentration was observed. It is thus unlikely that PGE or PGF alpha is an important determinant of PRA release during exercise, although circulating levels of PGE and PGF alpha do not necessarily reflect release rate or activity in the kidney.
在11名高血压患者进行的不间断分级自行车测力计运动试验中，测量了血浆前列腺素（PGE和PGFα）、儿茶酚胺浓度以及血浆肾素活性（PRA）。在卧位休息30分钟后、坐位休息15分钟后以及运动试验的最终工作负荷（平均为143±16.5W）时，从肱动脉和肺动脉采集血液。运动并未引起这些血浆PGE或PGFα浓度的显著变化，然而观察到动脉PRA和（去）肾上腺素浓度升高（P＜0.001）。因此，PGE或PGFα不太可能是运动期间PRA释放的重要决定因素，尽管PGE和PGFα的循环水平不一定反映肾脏中的释放速率或活性。
