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[不同接种途径与检测方法的比较研究。以一种灭活细菌疫苗为例]

[Comparative study of various routes of vaccination and testing. An instance of a killed bacterial vaccine].

作者信息

Binder P, du Colombier P, Bureau Fontanges R

出版信息

Poumon Coeur. 1982;38(5):317-23.

PMID:6760155
Abstract

The efficiency of intranasal subcutaneous, aerosol and digestive vaccinations with killed Klebsiella pneumoniae as vaccine was studied on the survival curves after experimental disease with pathogen K. pneumoniae I inoculated by the same routes. Results show that the local immunization is an important factor of protection and the intranasal route is very convenient.

摘要

以灭活肺炎克雷伯菌作为疫苗，通过鼻内、皮下、气溶胶和消化道途径接种疫苗，研究其在经相同途径接种肺炎克雷伯菌I病原体引发实验性疾病后的存活曲线。结果表明，局部免疫是保护的重要因素，鼻内途径非常便捷。

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