Buiuc D, Burcoveanu C
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1982 Jul-Sep;27(3):157-65.
The authors review: 1. The frequency of resistance to antibiotics among the H. influenzae populations, outlining the geographical areas representative of the evolution of the phenomenon. 2. The mechanisms and phenotypical peculiarities of the resistance of H. influenzae to antibiotics, emphasizing the peculiarities of its behaviour to beta-lactam antibiotics, with implications in the diagnosis and correct treatment of the infection. 3. Genetic mechanisms of resistance and hypothesis regarding the natural evolution of H. influenzae resistance to antibiotics. 4. Conclusions concerning the diagnosis and treatment of influenza today: methods for testing the infectious strains, associated antibiotherapy and new election antibiotics.