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[从流感嗜血杆菌对抗生素的耐药性角度来看]

[Haemophilus influenzae from the point of view of its resistance to antibiotics].

作者信息

Buiuc D, Burcoveanu C

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1982 Jul-Sep;27(3):157-65.

PMID:6760345
Abstract

The authors review: 1. The frequency of resistance to antibiotics among the H. influenzae populations, outlining the geographical areas representative of the evolution of the phenomenon. 2. The mechanisms and phenotypical peculiarities of the resistance of H. influenzae to antibiotics, emphasizing the peculiarities of its behaviour to beta-lactam antibiotics, with implications in the diagnosis and correct treatment of the infection. 3. Genetic mechanisms of resistance and hypothesis regarding the natural evolution of H. influenzae resistance to antibiotics. 4. Conclusions concerning the diagnosis and treatment of influenza today: methods for testing the infectious strains, associated antibiotherapy and new election antibiotics.

摘要

作者们回顾了

  1. 流感嗜血杆菌群体中抗生素耐药的频率,概述了代表该现象演变的地理区域。2. 流感嗜血杆菌对抗生素耐药的机制和表型特征,强调其对β-内酰胺类抗生素的行为特点,这对感染的诊断和正确治疗具有重要意义。3. 耐药的遗传机制以及关于流感嗜血杆菌抗生素耐药自然演变的假说。4. 当今流感诊断与治疗的结论:检测感染菌株的方法、相关抗菌疗法及新的可选抗生素。

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