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新生羔羊肾周脂肪组织中脂肪酸合成的体外发育

Development in vitro of fatty acid synthesis in perirenal adipose tissue from new-born lambs.

作者信息

Vernon R G

出版信息

Biol Neonate. 1982;42(5-6):275-8. doi: 10.1159/000241609.

DOI:10.1159/000241609
PMID:6760910
Abstract

Pieces of perirenal adipose tissue from new-born lambs were maintained in tissue culture for 5 days in the presence of insulin. During this period there was a 7-fold increase in the rate of fatty acid synthesis. Both omission of insulin from the culture medium and addition of ovine growth hormone to the culture medium resulted in a significantly lower rate of fatty acid synthesis. The results are compared with changes in the rate of fatty acid synthesis in vivo in neonatal lambs and the probable roles of insulin and growth hormone in the regulation of fatty acid synthesis in neonatal lambs are discussed.

摘要

将新生羔羊的肾周脂肪组织块在胰岛素存在的情况下进行组织培养5天。在此期间,脂肪酸合成速率增加了7倍。从培养基中去除胰岛素以及向培养基中添加绵羊生长激素均导致脂肪酸合成速率显著降低。将这些结果与新生羔羊体内脂肪酸合成速率的变化进行了比较,并讨论了胰岛素和生长激素在新生羔羊脂肪酸合成调节中的可能作用。

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