Usefulness of multiaxis echocardiography in assessment of the left ventricle in ischemic heart disease. A review.

Echoventriculography, a multiaxis M-mode echocardiographic technique, was developed to examine in detail the regional wall motions of the left ventricle. The basic technical aspects and limitations are described, and experience is reviewed on 263 healthy subjects or patients with ischaemic heart disease. The reliability in detecting site and size of asynergic segments was excellent as related to electrocardiographic and thallium scintigraphic sites of acute infarction, and with left ventricular cineangiograms in chronic coronary heart disease. The correlation with pathologic anatomic size of infarct in 24 consecutive patients was r = 0.88 (p less than 0.001) when expressed by a percentage of the left ventricular horizontal circumference. 94% of 111 infarcted segments were correctly detected by echo; only the posteroseptal and the most lateral regions remain out of the methodological range. The method separated old infarct scars from fresh necrosis. Decreasing echo contraction index correlated with increasing severity of coronary obstructions in 43 patients studied for coronary artery surgery. In 15 infarct patients the M-mode technique was more sensitive than two-dimensional echocardiography in recording asynergic segments or endocardial echoes. The multiple segmental echoventriculographic index decreased parallel with clinical severity of acute infarction (r = -0.79, p less than 0.001; 30 patients). There was a 88% (p less than 0.01) concordance between the reduction of the ST segments (-30%) and the recovery of the mechanical function in the ischaemic myocardial segments (+26%) after beta blockade with pindolol in 22 patients with acute infarction. Methylprednisolone showed no improvement. With dopamine the left ventricular size decreased markedly (p less than 0.0005). Echoventriculography thus seems to be very informative in evaluation of chronic or acute left ventricular dysfunction, despite the rather demanding nature of the technique in practice.