Osmanliev P, Lisichkov G
Vutr Boles. 1978;17(3):36-41.
Hemorrhagic manifestations were found in 142 (66.6%) out of 213 followed up patients with hypo- and aplastic anemia. Detailed clinical-laboratory study on the hemorrhagic syndrome was conducted in 58 of them. The hemorrhagic manifestations display a considerable polymorphism, being present both at the onset of the disease and its course. Changes in the laboratory tests were also found, associated mainly with thrombocytopenia. The tests, reflecting coagulation states, were most often normal. In four of the patients, hemorrhagia was due to disseminated intravasal coagulation. No correlation was found between granulocyte number and Factor VIII level.
在213例接受随访的低增生性和再生障碍性贫血患者中，142例（66.6%）出现出血表现。对其中58例患者进行了关于出血综合征的详细临床实验室研究。出血表现具有相当大的多态性，在疾病发作期和病程中均有出现。还发现实验室检查有变化，主要与血小板减少有关。反映凝血状态的检查大多正常。4例患者的出血是由于弥散性血管内凝血。未发现粒细胞数量与凝血因子VIII水平之间存在相关性。
