Zazgornik J, Kokot F, Pietrek J, Schmidt P, Kopsa H
Wien Klin Wochenschr. 1978 Jul 14;90(14):496-9.
Skeletal radiological changes were analyzed in 22 patients treated by chronic haemodialysis. Furthermore, the serum parathormone and 25-hydroxycholecalciferol concentrations were determined. X-ray evidence of renal osteopathy was found in 13 patients (59%). Extraskeletal calcification, subperiostal erosions and cystoids were the predominant lesions. Serum iPTH concentrations were increased in 21 out of 22 haemodialyzed patients. The serum 25-hydroxycholecalciferol concentration was normal. The results of this study seem to indicate that other factors apart from secondary hyperparathyroidism have a share in the development of renal osteopathy in patients on chronic haemodialysis.
对22例接受慢性血液透析治疗的患者的骨骼放射学变化进行了分析。此外,还测定了血清甲状旁腺激素和25-羟基胆钙化醇浓度。13例患者(59%)有肾性骨病的X线证据。骨外钙化、骨膜下侵蚀和囊肿样变是主要病变。22例血液透析患者中有21例血清iPTH浓度升高。血清25-羟基胆钙化醇浓度正常。本研究结果似乎表明,除继发性甲状旁腺功能亢进外,其他因素也参与了慢性血液透析患者肾性骨病的发生。