Burrow G N, Mujtaba Q, LiVolsi V, Cornog J
Yale J Biol Med. 1978 Jan-Feb;51(1):13-7.
Two hundred and three patients with single thyroid nodules were referred for radioactive scan of the thyroid. Solitary "cold" nodules were identified in 130 patients and 68 of these patients came to surgery. Of this group, 12 patients were found to have carcinoma. There was no obvious selection process which distinguished the 68 patients who underwent surgery from the 62 who did not. There is a significant risk of thyroid neoplasms occurring in patients with solitary "cold" nodules, and this is particularly true in patients under forty.
203例患有单个甲状腺结节的患者被转诊接受甲状腺放射性扫描。130例患者发现有孤立性“冷”结节,其中68例患者接受了手术。在这组患者中,有12例被发现患有癌症。在接受手术的68例患者和未接受手术的62例患者之间,没有明显的区分选择过程。孤立性“冷”结节患者发生甲状腺肿瘤的风险很高,在40岁以下的患者中尤其如此。