Maiti B R, Chakraborty S, Boral A
Arch Histol Jpn. 1982 Dec;45(5):449-52. doi: 10.1679/aohc.45.449.
A histological investigation was made to elucidate whether mammalian (ovine) prolactin can induce mitotic activity in pancreatic islet cell (in splenic lobe) of chicks. Prolactin treatment in different dosages (total dosage: 15, 50 and 100 IU per bird in 10 days) increased the mitotic frequency and also caused hypertrophy in the AF-positive cells of the B-islets in the splenic lobe. The increase in mitotic frequency was uniform for all doses applied. It is suggested that prolactin has a mitogenic action on the pancreatic islet cells of male chicks and that action is possibly not dose-dependent.
进行了一项组织学研究，以阐明哺乳动物（绵羊）催乳素是否能诱导雏鸡胰腺胰岛细胞（脾叶中的）有丝分裂活性。不同剂量的催乳素处理（总剂量：每只鸡在10天内为15、50和100国际单位）增加了有丝分裂频率，并且还导致脾叶中B胰岛的AF阳性细胞肥大。所有应用剂量的有丝分裂频率增加都是一致的。提示催乳素对雄性雏鸡的胰腺胰岛细胞有促有丝分裂作用，且该作用可能与剂量无关。
