Cultures were done for 14.838 cerebro spinal fluid specimens (CSF) during 1977-1980. Positive results were obtained from 950 specimens. These were identified as 352 Klebsiella-Enterobacter (37.0%), 133 Pseudomonas (14.%), 96 Salmonella (10.1%), 65 Pneumococcus (6,9%), 51 Escherichia coli 5,4%), 50 Meningococcus (.3%), Haemophilus influenzae type B (1.0%) and 127 various miscellaneous bacteria. During the same period of time, total of Salmonella isolations from various sources were 865. These specimens were 488 stool (57.0%), 160 blood (18.6% 7) 96 CSF (11.2%) so forth. The majority of these Salmonella strains were of typhimurium serotype carrying a known antibiotic resistence plasmid. This plasmid, belonging to the fime compatibility group, present in the Salmonella typhimurium strains isolated in Middle-East countries like Iran, Israel and others, conferred resistance to the carrying strain against antibiotics like ampicillin, kanamycin, chloramphenicol, streptomycin, sulphamide and tetracycline. As started to show up in Ankara too, addition of trimethoprim and gentamicin resistences to this markers were reported. These bacteria were also causing epidemics in pediatric wards of some South America countries which develops with hing rate of bacteremia and meningitis complications as it is in our hospital.
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