Jasonni V M, Bulletti C, Cristiani P, Fuschini G, Ferraretti A P, Bonavia M, Flamigni C
Acta Eur Fertil. 1982 Jun;13(2):101-4.
Estrogen provocation test was performed in 27 women with hypothalamic chronic anovulation: all patients received I mg of estradiol benzoate (EB) as a single im injection. Plasma 17-beta-estradiol (E2) levels were monitored during the test performed and then compared; no significant correlation was found between mean basal values of LH and E2 and the LH peak response (r = 0.246, P = 0.108 for LH; r = 0.124, P = 0.278 for E2). These data seem to indicate that basal LH values reflect the tonic secretion but not the hypothalamic responsiveness to the estrogen positive feedback; moreover, this latter seems not be influenced by the endogenous E2 levels.
对27名下丘脑慢性无排卵女性进行了雌激素激发试验：所有患者均单次肌肉注射1毫克苯甲酸雌二醇（EB）。在试验过程中监测血浆17-β-雌二醇（E2）水平，然后进行比较；LH和E2的平均基础值与LH峰值反应之间未发现显著相关性（LH的r = 0.246，P = 0.108；E2的r = 0.124，P = 0.278）。这些数据似乎表明，基础LH值反映的是持续性分泌，而非下丘脑对雌激素正反馈的反应性；此外，后者似乎不受内源性E2水平的影响。
