Pull C B, Dreyfus J F, Brun J P
Int Pharmacopsychiatry. 1982;17 Suppl 2:205-9.
This investigation compares the effects of single and double doses of nitrazepam (5 and 10 mg) and zopiclone (7.5 and 15 mg) and placebo for 1 night in 40 psychiatric patients. The results indicate that zopiclone is an active hypnotic compound, comparable in its effects to those of nitrazepam, the higher dosage being best adapted to the type of patients included in the study.
本研究比较了单剂量和双剂量的硝西泮(5毫克和10毫克)、佐匹克隆(7.5毫克和15毫克)及安慰剂对40名精神科患者1晚的影响。结果表明,佐匹克隆是一种有效的催眠化合物,其效果与硝西泮相当,较高剂量最适合该研究中的患者类型。