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[使用传统血液透析器进行的短期透析]

[Short-term dialyses using a conventional hemodialyzer].

作者信息

Válek A, Dzúrik R, Bozek P, Válková D

出版信息

Z Urol Nephrol. 1978 May;71(5):329-38.

PMID:676537
Abstract
  1. Twelve patients who were treated twice eight hours a week for at least one year were admitted to a dialysis plan of twice seven hours a week and fourteen patients who were dialysed twice eight hours a week for at least one year were dialysed thrice four hours a week. The patients were dialysed with a spool dialysator with cuprophan membrane of a surface of 1 m2. Blood flow was 200--250 ml/min., dialysate flow 500 ml/min. After 3, 6, 10, and 12 months the clinical picture, hydratation, protein katabolism, degree of anaemia and renal osteodystrophy as well as number of complications, degree of rehabilitation, concentration of the medium-molecular substances and of phenylalanine and the glucose tolerance were compared and the opinion of the patients concerning different types of the plan of dialysis was inquired. 2. The plan of dialysis of thrice four hours a week with a conventional dialysator is sufficient for a good state of the most patients. In none of the parameters investigated by us we could establish noticeable differences between the dialysis plan twice eight hours and twice seven hours and thrice four hours a week. The patients themselves clearly preferred a plan of dialysis of thrice four hours a week. 3. The concentration of medium-molecular substances in the blood is no sufficiently sensitive indicator for the determination of the quality of a permanent dialysis treatment in a good clinical state of the patient.
摘要
  1. 12名每周接受两次8小时透析治疗至少一年的患者进入每周两次7小时的透析方案,14名每周接受两次8小时透析治疗至少一年的患者改为每周三次4小时透析。患者使用表面积为1平方米的铜仿膜卷轴透析器进行透析。血流量为200 - 250毫升/分钟,透析液流量为500毫升/分钟。在3、6、10和12个月后,对临床症状、水合作用、蛋白质分解代谢、贫血程度和肾性骨营养不良以及并发症数量、康复程度、中分子物质和苯丙氨酸浓度以及葡萄糖耐量进行了比较,并询问了患者对不同透析方案的看法。2. 使用传统透析器每周三次4小时的透析方案对大多数患者的良好状态来说是足够的。在我们所研究的参数中,我们未能发现每周两次8小时、每周两次7小时和每周三次4小时的透析方案之间存在明显差异。患者自己明显更喜欢每周三次4小时的透析方案。3. 血液中中分子物质的浓度对于判断患者临床状态良好时长期透析治疗的质量来说不是一个足够敏感的指标。

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