静脉注射硝酸甘油对一例变异型心绞痛患者的有益作用。
Beneficial effects of intravenous glyceryl trinitrate in a case of Prinzmetal angina.
作者信息
Antman E, Gunther S, Barry W
出版信息
Br Heart J. 1980 Jan;43(1):88-91. doi: 10.1136/hrt.43.1.88.
Abstract
A case is described of the successful use of intravenous glyceryl trinitrate in controlling ischaemia-induced high-grade ventricular ectopic activity occurring in a patient during a Prinzmetal angina attack. The intravenous form of glyceryl trinitrate is probably more effective than the sublingual form in controlling arrhythmias arising during acute ischaemic episodes because of prompt delivery of the drug to the coronary circulation where vasodilation occurs. In addition,the ability to control the quantity and rate of drug delivery with an intravenous infusion offers distinct advantages in cases of coronary spasm occurring during situations such as coronary arteriography where it can be administered with careful electrocardiographic and haemodynamic monitoring.
摘要
本文描述了一例成功使用静脉注射硝酸甘油控制变异型心绞痛发作时患者出现的缺血性高度室性异位活动的病例。静脉注射硝酸甘油在控制急性缺血发作时出现的心律失常方面可能比舌下含服更有效，因为药物能迅速输送到发生血管舒张的冠状动脉循环。此外，在冠状动脉造影等情况下发生冠状动脉痉挛时，通过静脉输注控制药物输送的量和速度的能力具有明显优势，此时可在仔细的心电图和血流动力学监测下给药。
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Br Heart J. 1980 Jan;43(1):88-91. doi: 10.1136/hrt.43.1.88.
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