Notelovitz M
Geriatrics. 1980 Apr;35(4):113-24.
The most significant indications for estrogen therapy in women over 60 are symptoms related to the vagina, bladder, and bones. But before starting therapy, make certain these symptoms are directly related to estrogen deprivation, and not to the aging process. In patients on long-term therapy, use the lowest dose of estrogen plus progestogen that will alleviate the symptoms in the shortest period of time. Patients should be carefully monitored to reduce the risk of endometrial carcinoma.
60岁以上女性雌激素治疗的最显著指征是与阴道、膀胱和骨骼相关的症状。但在开始治疗前，要确定这些症状与雌激素缺乏直接相关，而非与衰老过程有关。对于长期治疗的患者，使用能在最短时间内缓解症状的最低剂量雌激素加孕激素。应仔细监测患者以降低子宫内膜癌的风险。
