氨氯吡咪对蟾蜍膀胱电导率的影响。

Effect of amiloride on conductance of toad urinary bladder.

作者信息

Gordon L G

出版信息

J Membr Biol. 1980 Jan 31;52(1):61-7. doi: 10.1007/BF01869006.

Abstract

The transepithelial conductance of toad bladder epithelia and the amplitude of the fluctuations of this conductance caused by the action of the underlying smooth muscle have been further investigated. In particular, amiloride was found to reduce both tissue conductance and its fluctuating component to the same extent. Analysis suggests that the steady-state conductance of the toad urinary bladder may be associated only with the paracellular pathway for ions.

摘要

对蟾蜍膀胱上皮的跨上皮电导以及由其下方平滑肌作用引起的该电导波动幅度进行了进一步研究。特别地，发现氨氯吡咪能同等程度地降低组织电导及其波动成分。分析表明，蟾蜍膀胱的稳态电导可能仅与离子的细胞旁途径有关。