氨氯地平对钠转运的抑制作用降低了紧密上皮细胞基底外侧膜的钾离子电导。
Sodium transport inhibition by amiloride reduces basolateral membrane potassium conductance in tight epithelia.
作者信息
Davis C W, Finn A L
出版信息
Science. 1982 Apr 30;216(4545):525-7. doi: 10.1126/science.7071599.
PMID:7071599
Abstract
In toad and frog urinary bladder, electrophysiological data suggest that inhibition of transepithelial sodium transport by mucosal amiloride results in a decrease in basolateral membrane conductance. These results were confirmed by showing that amiloride addition caused a decrease in basolateral membrane potassium permeability.
摘要
在蟾蜍和青蛙的膀胱中，电生理数据表明，黏膜用氨氯吡脒抑制跨上皮钠转运可导致基底外侧膜电导降低。通过证明添加氨氯吡脒会导致基底外侧膜钾通透性降低，这些结果得到了证实。
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