痘苗病毒宿主范围限制分子机制中的细胞差异
Cellular differences in the molecular mechanisms of vaccinia virus host range restriction.
作者信息
Hruby D E, Lynn D L, Condit R C, Kates J R
出版信息
J Gen Virol. 1980 Apr;47(2):485-8. doi: 10.1099/0022-1317-47-2-485.
PMID:6767809
Abstract
The biochemistry of vaccinia virus replication in two permissive (BSC-40, L-929), and two non-permissive (CHO, MDBK) cell lines has been compared. While CHO and MDBK cells differentially allowed expression of the various stages in the vaccinia developmental programme, neither cell supported production of any infectious progeny virions.
摘要
已对痘苗病毒在两种允许性细胞系（BSC - 40、L - 929）和两种非允许性细胞系（CHO、MDBK）中复制的生物化学过程进行了比较。虽然CHO和MDBK细胞对痘苗病毒发育程序中各个阶段的表达表现出差异，但两种细胞均不支持产生任何有感染性的子代病毒粒子。
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