Rieth K G, Fujiwara K, Di Chiro G, Klatzo I, Brooks R A, Johnston G S, O'Connor C M, Mitchell L G
Radiology. 1980 May;135(2):343-8. doi: 10.1148/radiology.135.2.6768102.
Vasogenic cerebral edema was induced cryogenically in rhesus monkeys. Serial scans in both axial and coronal planes were used to study the onset, peak, and regression of edema. Progression of edema, predominantly involving the white matter, was analyzed from the postmortem distribution of a blood/brain barrier indicator (Evans blue) injected at surgery. Specific gravity was measured in fresh, unfixed specimens from both the edematous and normal hemispheres and correlated with corresponding CT attenuation values obtained before death. The drop in specific gravity closely corresponded to the decrease in CT attenuation.
在恒河猴中通过低温诱导血管源性脑水肿。使用轴向和冠状面的系列扫描来研究水肿的发生、峰值和消退。从手术时注射的血脑屏障指示剂（伊文思蓝）的死后分布分析主要累及白质的水肿进展情况。在来自水肿半球和正常半球的新鲜、未固定标本中测量比重，并将其与死亡前获得的相应CT衰减值相关联。比重的下降与CT衰减的降低密切对应。
