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A mutant Ebg enzyme that converts lactose into an inducer of the lac operon.
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Transgalactosylation activity of ebg beta-galactosidase synthesizes allolactose from lactose.
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Evolution of a regulated operon in the laboratory.
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Control of lactose transport in Escherichia coli.
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Lactose metabolism involving phospho-beta-galactosidase in Klebsiella.
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DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes.
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The anomeric specificity of beta-galactosidase and lac permease from Escherichia coli.
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Lactose permeation via the arabinose transport system in Escherichia coli K-12.
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Lac repressor-operator interaction. 8. Lactose is an anti-inducer of the lac operon.
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引用本文的文献
1
Evolution of a regulated operon in the laboratory.
Genetics. 1982 Jul-Aug;101(3-4):335-44. doi: 10.1093/genetics/101.3-4.335.
2
Transgalactosylation activity of ebg beta-galactosidase synthesizes allolactose from lactose.
J Bacteriol. 1982 Apr;150(1):132-40. doi: 10.1128/jb.150.1.132-140.1982.
3
DNA sequence analysis of artificially evolved ebg enzyme and ebg repressor genes.
Genetics. 1989 Dec;123(4):635-48. doi: 10.1093/genetics/123.4.635.
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A SPECTROPHOTOMETRIC ASSAY FOR THIOGALACTOSIDE TRANSACETYLASE.
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Transport systems for galactose and galactosides in Escherichia coli. II. Substrate and inducer specificities.
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Lactose permeation via the arabinose transport system in Escherichia coli K-12.
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Regulation of newly evolved enzymes. I. Selection of a novel lactase regulated by lactose in Escherichia coli.
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lac Repressor-operator interaction. VI. The natural inducer of the lac operon.
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Regulation of newly evolved enzymes. II. The ebg repressor.
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Experimental evolution of a new enzymatic function. Kinetic analysis of the ancestral (ebg) and evolved (ebg) enzymes.
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Methyl galactosidase activity: an alternative evolutionary destination for the ebgA0 gene.
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A mutation allowing utilisation of lactose by Escherichia coli lacY mutants defective in lactose permease.
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