一种将乳糖转化为乳糖操纵子诱导物的突变型Ebg酶。
A mutant Ebg enzyme that converts lactose into an inducer of the lac operon.
作者信息
Rolseth S J, Fried V A, Hall B G
出版信息
J Bacteriol. 1980 Jun;142(3):1036-9. doi: 10.1128/jb.142.3.1036-1039.1980.
Abstract
Lactose is not itself an inducer of the lac operon, nor is it converted to an inducer by ebg+ beta-galactosidase of Escherichia coli. We report here the isolation of a mutant Ebg beta-galactosidase which is capable of converting lactose into an inducer of the lac operon.
摘要
乳糖本身并不是乳糖操纵子的诱导物，它也不能被大肠杆菌的ebg⁺β-半乳糖苷酶转化为诱导物。我们在此报告一种突变型Ebgβ-半乳糖苷酶的分离，该酶能够将乳糖转化为乳糖操纵子的诱导物。
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引用本文的文献
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Evolution of a regulated operon in the laboratory.实验室中一个调控操纵子的进化。
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Genetics. 1989 Dec;123(4):635-48. doi: 10.1093/genetics/123.4.635.
本文引用的文献
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[ROLE OF LACTOSE AND ITS METABOLIC PRODUCTS IN THE INDUCTION OF THE LACTOSE OPERON IN ESCHERICHIA COLI].[乳糖及其代谢产物在大肠杆菌乳糖操纵子诱导中的作用]
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A SPECTROPHOTOMETRIC ASSAY FOR THIOGALACTOSIDE TRANSACETYLASE.硫代半乳糖苷转乙酰酶的分光光度测定法。
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Transport systems for galactose and galactosides in Escherichia coli. II. Substrate and inducer specificities.大肠杆菌中半乳糖和半乳糖苷的转运系统。II. 底物和诱导剂特异性。
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Lactose permeation via the arabinose transport system in Escherichia coli K-12.通过大肠杆菌K-12中的阿拉伯糖转运系统进行乳糖渗透。
J Bacteriol. 1974 Oct;120(1):266-72. doi: 10.1128/jb.120.1.266-272.1974.
5
Regulation of newly evolved enzymes. I. Selection of a novel lactase regulated by lactose in Escherichia coli.新进化酶的调控。I. 大肠杆菌中受乳糖调控的新型乳糖酶的筛选
Genetics. 1974 Mar;76(3):391-400. doi: 10.1093/genetics/76.3.391.
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lac Repressor-operator interaction. VI. The natural inducer of the lac operon.乳糖阻遏蛋白-操纵基因相互作用。VI. 乳糖操纵子的天然诱导物。
J Mol Biol. 1972 Aug 28;69(3):397-408. doi: 10.1016/0022-2836(72)90253-7.
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A mutation allowing utilisation of lactose by Escherichia coli lacY mutants defective in lactose permease.
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