Szpunar W E, Block M, Bednarz M N, Stoffer S S
J Nucl Med. 1980 Jun;21(6):576-8.
The free thyroxine (FT4) test of Clinical Assays, Corning Medical, and Damon Diagnostics were evaluated in 245 patients. Although all three assays generally correlated well with the clinical functional status, there were apparent discrepancies in the clinically euthyroid population. All patients with discordant values had either relatively high or low triiodothyronine (T3) uptakes. In these instances, the free-thyroxine index gave a more accurate assessment of the clinical thyroid status than did the FT4. In our opinion, these findings place a critical limitation on these assays as a replacement for the free-thyroxine index.
对康宁医疗公司（Clinical Assays）、达蒙诊断公司（Damon Diagnostics）的游离甲状腺素（FT4）检测方法进行了245例患者的评估。虽然这三种检测方法总体上与临床功能状态相关性良好，但在临床甲状腺功能正常人群中存在明显差异。所有检测值不一致的患者，其三碘甲状腺原氨酸（T3）摄取率相对较高或较低。在这些情况下，游离甲状腺素指数比FT4能更准确地评估临床甲状腺状态。我们认为，这些发现严重限制了这些检测方法替代游离甲状腺素指数的应用。
