Pearl M, Boxt L M
Radiology. 1980 Jul;136(1):83-4. doi: 10.1148/radiology.136.1.6770416.
Because lead crosses the placenta throughout pregnancy, the fetus is at risk for lead poisoning. A full term, asymptomatic child was born with congenital lead poisoning secondary to maternal pica. Radiographic findings of a dense cranial vault, lead lines, and delayed skeletal and deciduous dental development were noted at birth. After chelation therapy, when the patient was seven months old, radiographs revealed normal skeletal maturation. Tooth eruption did not occur until 15 months of age. Newborn infants with these radiographic findings should be screened for subclinical, congenital lead poisoning.
由于铅在整个孕期都会穿过胎盘，胎儿有铅中毒的风险。一名足月、无症状的儿童因母亲异食癖而出生时患有先天性铅中毒。出生时发现有颅骨致密、铅线以及骨骼和乳牙发育延迟的影像学表现。螯合治疗后，患儿7个月大时，X光片显示骨骼成熟正常。直到15个月大时才开始出牙。有这些影像学表现的新生儿应进行亚临床先天性铅中毒筛查。
