铁粒幼细胞性贫血作为霍奇金病治疗患者的白血病前期事件。

Sideroblastic anemia as a preleukemic event in patients treated for Hodgkin's disease.

作者信息

Kitahara M, Cosgriff T M, Eyre H J

出版信息

Ann Intern Med. 1980 May;92(5):625-7. doi: 10.7326/0003-4819-92-5-625.

Abstract

Sideroblastic anemia after treatment for Hogdkin's disease was seen in two patients 3 years after completion of radiation therapy and chemotherapy. This was followed in both by the development of myelomonoblastic leukemia. No evidence of recurrent Hodgkin's disease was present in either patient. Our observation suggests that development of sideroblastic anemia in patients previously treated for Hodgkin's disease is probably secondary to the treatment and is a preleukemic event.

摘要

两名霍奇金病患者在完成放疗和化疗3年后出现了铁粒幼细胞性贫血。随后两人均发展为骨髓单核细胞白血病。两名患者均无霍奇金病复发的证据。我们的观察表明，既往接受过霍奇金病治疗的患者出现铁粒幼细胞性贫血可能是治疗的继发性结果，并且是白血病前期事件。