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In vivo administration of hydroxylated phenobarbital metabolites: effect on rat hepatic cytochromes P-450, epoxide hydrolase and UDP-glucuronosyltransferase.

作者信息

Cresteil T, Mahu J L, Dansette P M, Leroux J P

出版信息

Biochem Pharmacol. 1980 Apr 15;29(8):1127-33. doi: 10.1016/0006-2952(80)90407-4.

DOI:10.1016/0006-2952(80)90407-4
PMID:6770872
Abstract
摘要

相似文献

1
In vivo administration of hydroxylated phenobarbital metabolites: effect on rat hepatic cytochromes P-450, epoxide hydrolase and UDP-glucuronosyltransferase.体内给予羟基化苯巴比妥代谢物：对大鼠肝细胞色素P-450、环氧化物水解酶和UDP-葡萄糖醛酸基转移酶的影响。
Biochem Pharmacol. 1980 Apr 15;29(8):1127-33. doi: 10.1016/0006-2952(80)90407-4.
2
Comparison of the effects of phenobarbital and its hydroxylated metabolites on drug-metabolizing enzymes during ontogenesis.苯巴比妥及其羟基化代谢产物在个体发育过程中对药物代谢酶影响的比较。
Pediatr Pharmacol (New York). 1981;1(4):331-40.
3
The in vivo effect of benzamide and phenobarbital on liver enzymes: poly(ADP-ribose) polymerase, cytochrome P-450, styrene oxide hydrolase, cholesterol oxide hydrolase, glutathione S-transferase and UDP-glucuronyl transferase.苯甲酰胺和苯巴比妥对肝脏酶的体内作用：聚（ADP - 核糖）聚合酶、细胞色素P - 450、环氧苯乙烯水解酶、胆固醇氧化物水解酶、谷胱甘肽S - 转移酶和UDP - 葡萄糖醛酸基转移酶。
Biochem Biophys Res Commun. 1984 Jul 31;122(2):770-5. doi: 10.1016/s0006-291x(84)80100-x.
4
Electroimmunochemical quantitation of cytochrome P-450, cytochrome P-448, and epoxide hydrolase in rat liver microsomes.大鼠肝微粒体中细胞色素P-450、细胞色素P-448和环氧化物水解酶的电免疫化学定量分析。
J Biol Chem. 1981 Aug 25;256(16):8815-20.
5
Induction of hepatic cytochrome P-450c-dependent monooxygenase activities by dantrolene in rat.
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6
Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin.大鼠皮肤中细胞色素P-450、环氧化物代谢酶和尿苷二磷酸葡萄糖醛酸基转移酶不同形式的表征。
Biochem Pharmacol. 1989 Jul 1;38(13):2187-94. doi: 10.1016/0006-2952(89)90075-0.
7
Altered activation/detoxication enzymology following neonatal diethylstilbestrol treatment.新生儿己烯雌酚治疗后激活/解毒酶学的改变。
J Biochem Toxicol. 1988 Summer;3:87-103. doi: 10.1002/jbt.2570030204.
8
The in vivo toxicity of CS2 to liver microsomes: binding of labelled CS2 and changes of the microsomal enzyme activities.二硫化碳对肝微粒体的体内毒性：标记二硫化碳的结合及微粒体酶活性的变化。
Acta Pharmacol Toxicol (Copenh). 1977 Feb;40(2):329-36. doi: 10.1111/j.1600-0773.1977.tb02085.x.
9
Effect of 1-benzylimidazole on cytochromes P-450 induction and on the activities of epoxide hydrolases and UDP-glucuronosyltransferases in rat liver.
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10
[Ingestion of soybean epoxide oil. Effects on monooxygenases, epoxide hydrolase and activities of UDP glucuronosyltransferases in hepatic microsomes of the rat].[大豆环氧油的摄入。对大鼠肝微粒体中单加氧酶、环氧水解酶及尿苷二磷酸葡萄糖醛酸基转移酶活性的影响]
C R Seances Soc Biol Fil. 1988;182(1):105-17.

引用本文的文献

1
On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations.关于化学物质对细胞色素 P450 酶的选择性诱导的一般机制：一些理论上的考虑。
Expert Opin Drug Metab Toxicol. 2010 Apr;6(4):483-94. doi: 10.1517/17425250903578642.
2
The effect of phenobarbital on the transcriptional activity of liver.苯巴比妥对肝脏转录活性的影响。
Biochem J. 1983 Feb 15;210(2):599-606. doi: 10.1042/bj2100599.
3
Demonstration by in situ hybridization of the zonal modulation of rat liver cytochrome P-450b and P-450e gene expression after phenobarbital.
苯巴比妥处理后大鼠肝脏细胞色素P-450b和P-450e基因表达区域调节的原位杂交显示
J Clin Invest. 1988 Aug;82(2):658-66. doi: 10.1172/JCI113645.
4
Aminopyrine-N-demethylase. I. Directed modification of substrates' structure as a way of production of inducer of the monooxygenase isoform P-450b.氨基比林 -N-脱甲基酶。I. 作为生产单加氧酶同工型P - 450b诱导剂的一种方式对底物结构进行定向修饰。
Eur J Drug Metab Pharmacokinet. 1991 Jul-Sep;16(3):207-12. doi: 10.1007/BF03189961.
5
Phenobarbital induction of cytochrome P-450 gene expression.苯巴比妥对细胞色素P-450基因表达的诱导作用。
Biochem J. 1992 Feb 1;281 ( Pt 3)(Pt 3):577-92. doi: 10.1042/bj2810577.