Lejeune F J, Van Hoof G, Gerard A
Br J Surg. 1980 May;67(5):318-20. doi: 10.1002/bjs.1800670506.
Twenty-four patients presenting with primary malignant melanoma of the skin (stage 1) were submitted to wide excision of the tumour, followed by immediate split-skin grafting. In 12 patients a CO2 laser was used to excise the melanoma and only 1 of these patients had a 100 per cent skin graft take, while 9 out of 12 patients whose melanoma was exercised with a conventional scalpel had a 100 per cent take. It is concluded that skin excision with the CO2 laser impairs subsequent skin graft take.
24例原发性皮肤恶性黑色素瘤（1期）患者接受了肿瘤广泛切除术，随后立即进行了分层皮片移植。12例患者使用二氧化碳激光切除黑色素瘤，其中只有1例患者的皮片100%存活，而12例使用传统手术刀切除黑色素瘤的患者中有9例皮片100%存活。结论是，用二氧化碳激光进行皮肤切除会损害随后的皮片存活。
