Plenk H, Kyrle P, Fischer P L
Wien Klin Wochenschr. 1981 Apr 3;93(7):230-5.
The great advantages of CO2 laser surgery are the contact-less cutting and the haemostatic effect. An obliteration of blood- and lymph-vessels thus preventing tumour-cell mobilisation and metastatic spread is considered as most advantageous for tumour surgery. Basing on own morphological and experimental investigations, some of these advantages are critically discussed. The morphology of human skin incisions made by a CO2 laser is described, using light microscopy, and the wound healing process of laser incisions in the dorsal skin of rats is compared with incisions made by thermocautery and conventional scalpel. After contamination of laser and scalpel incisions with india-ink, the migration of these particles to the regional lymph-nodes was also investigated. Compared to the scalpel-incisions, the laser- and even more the thermocauter-incisions showed the well known delay in healing, due to the extensive tissue necrosis at the wound margins. This coagulation necrosis, however, was not obliterate the lymphatic drainage. It is concluded from these experiments that the use of the CO2 laser will not guarantee the prevention of metastatic spread and should mainly be recommended where the haemostatic effect is essential.
二氧化碳激光手术的巨大优势在于非接触式切割和止血效果。血管和淋巴管的闭塞从而防止肿瘤细胞移动和转移扩散,这被认为对肿瘤手术最为有利。基于自身的形态学和实验研究,对其中一些优势进行了批判性讨论。使用光学显微镜描述了由二氧化碳激光制作的人体皮肤切口的形态,并将大鼠背部皮肤激光切口的伤口愈合过程与热灼术和传统手术刀切口进行了比较。在用印度墨水污染激光和手术刀切口后,还研究了这些颗粒向区域淋巴结的迁移。与手术刀切口相比,激光切口,尤其是热灼术切口,由于伤口边缘广泛的组织坏死,显示出众所周知的愈合延迟。然而,这种凝固性坏死并未阻断淋巴引流。从这些实验得出的结论是,使用二氧化碳激光不能保证防止转移扩散,主要应在止血效果至关重要的情况下推荐使用。